Peripheral blood marker changes predict response and prognosis in locally advanced gastric cancer with neoadjuvant sintilimab plus XELOX

doi:10.4251/wjgo.122796

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Oct 15, 2026; 18(10): 122796
Published online Oct 15, 2026. doi: 10.4251/wjgo.122796

Table 1 Baseline clinical and pathological characteristics of patients (n = 39)

Characteristic	Median (range) or n (%)
Age (years)	64 (35-77)
Gender
Male	25 (64.1)
Female	14 (35.9)
Tumor differentiation
Poor	25 (64.1)
Moderate	14 (35.9)
Histological type
PC	15 (38.5)
Non-PC	24 (61.5)
Tumor location
Cardia	9 (23.1)
Gastric antrum	16 (41.0)
Gastric body	14 (35.9)
Lauren classification
Intestinal	18 (46.2)
Diffuse	21 (53.8)
cT
cT₃	16 (41.0)
cT₄	23 (59.0)
cN
cN₀	5 (12.8)
cN₁	17 (43.6)
cN₂	9 (23.1)
cN₃	8 (20.5)
pT
pT₀	6 (15.4)
pT₁	4 (10.3)
pT₂	8 (20.5)
pT₃	11 (28.2)
pT₄	10 (25.6)
pN
pN₀	21 (53.8)
pN₁	7 (17.9)
pN₂	1 (2.6)
pN₃	10 (25.6)
TRG
Grade 0	6 (15.4)
Grade 1	8 (20.5)
Grade 2	22 (56.4)
Grade 3	3 (7.7)

PC: Poorly cohesive gastric adenocarcinoma; TRG: Tumor regression grade.

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Citation: Wu Y, Xu MM, Wang GL, Du WD, Su XH. Peripheral blood marker changes predict response and prognosis in locally advanced gastric cancer with neoadjuvant sintilimab plus XELOX. World J Gastrointest Oncol 2026; 18(10): 122796
URL: https://www.wjgnet.com/1948-5204/full/v18/i10/122796.htm
DOI: https://dx.doi.org/10.4251/wjgo.122796

Wu Y, Xu MM, Wang GL, Du WD, Su XH. Peripheral blood marker changes predict response and prognosis in locally advanced gastric cancer with neoadjuvant sintilimab plus XELOX. World J Gastrointest Oncol 2026; 18(10): 122796 [DOI: 10.4251/wjgo.122796]

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