CHMP2A as a potential prognostic biomarker for esophageal squamous cell carcinoma promotes tumor angiogenesis and cancer progression

Figure 3 CHMP2A expression is associated with infiltration of multiple immune cells in esophageal squamous cell carcinoma. A: Correlation of CHMP2A with immune, estimate, and stromal as analyzed by the ESTIMATE algorithm; B and C: Relationship between CHMP2A expression and immune cells as elucidated by the single sample gene set enrichment analysis and CIBERSORT algorithms; D: Elevated CHMP2A expression inhibited the infiltration of multiple immune cells; E: Relationship between CHMP2A expression and immune checkpoint expression levels, including CD274 (PD-L1), CTLA4, HAVCR2, LAG3, PDCD1 LG2, PDCD1 (PD-1), SIGLEC15, and TIGIT. ^aP < 0.05; ^bP < 0.01. ssGSEA: Single sample gene set enrichment analysis; TPM: Transcripts per million.