CHMP2A as a potential prognostic biomarker for esophageal squamous cell carcinoma promotes tumor angiogenesis and cancer progression

Figure 2 CHMP2A expression is elevated in esophageal cancer and predicts poor prognosis. A and B: CHMP2A mRNA expression in esophageal cancer patients from The Cancer Genome Atlas data; C: Correlation of CHMP2A expression with N stage; D-F: Kaplan-Meier curves elucidate the correlation between CHMP2A expression and overall survival, disease-specific survival, and progression-free interval in patients with esophageal cancer; G: Nomogram showing patients with esophageal cancer projected to have 1-, 3-, and 5-year survival probability; H: Correction curve demonstrating the degree of agreement between predictions and actual observations; I: Receiver operating characteristic curve showing the diagnostic value of CHMP2A in patients with esophageal cancer. ^aP < 0.05; ^bP <0.01. AUC: Area under the curve; TPM: Transcripts per million; TPR: True positive rate; FPR: False positive rate.