CHMP2A as a potential prognostic biomarker for esophageal squamous cell carcinoma promotes tumor angiogenesis and cancer progression

Table 1 Correlation between CHMP2A expression and clinical-pathological parameters in patients with esophageal squamous cell carcinoma

Characteristics	n	CHMP2A		P value
		High	Low
Total	50	31	19
Gender				0.895
Male	31	19	12
Female	19	12	7
Age (year)				0.109
≤ 60	10	4	6
> 60	40	27	13
Size (cm)				0.777
< 4	33	20	13
≥ 4	17	11	6
Pathological grading				0.042
I-II	13	5	8
III	37	26	11
Lymph node metastasis				< 0.001
Yes	19	15	4
No	31	16	15
Venous invasion				0.011
Positive	15	11	4
Negative	35	12	23
Nerve infiltration				0.081
Positive	12	10	2
Negative	38	21	17
Differentiation				0.214
Well	23	15	8
Moderate	17	8	9
Poor	10	8	2
Smoking				0.085
Yes	18	14	4
No	32	17	15
Alcohol use				0.287
Yes	12	9	3
No	38	22	16
Family history				0.026
Yes	7	7	0
No	43	24	19