PARVA promotes gastric cancer progression through FBXO15-related PI3K/AKT signaling

Figure 4 PARVA overexpression promoted the proliferation, migration, and invasion of gastric cancer cells. A: Western blot analysis of PARVA overexpression efficiency in SGC7901 cells, with densitometric analysis; B: Colony formation assays with quantification of colony numbers; C: EdU assays; D: Quantification of EdU-positive cells; E: Transwell migration and invasion assays with quantification; F: Wound-healing assays with quantification of wound closure. When followed by a numeral, the comparison refers to the corresponding control within the indicated subgroup. respectively. ^aP < 0.01. ^bP < 0.001; ¹Comparison within the migration subgroup; ²Comparison within the invasion subgroup; ³Comparison within the 0 hour subgroup; ⁴Comparison within the 48 hours subgroup. NS: Not significant; NC: Negative control; OE: Overexpression.