Enterocloster bolteae drives hyperglycemia-associated colorectal cancer cell proliferation via Rac/Rho-MSH6-Elongin C signaling pathway

doi:10.4251/wjgo.119879

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World Journal of Gastrointestinal Oncology

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1948-5204

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Oct 15, 2026; 18(10): 119879
Published online Oct 15, 2026. doi: 10.4251/wjgo.119879

Table 2 Primer sequences used in this study, sourced from Primer Bank

Name		Sequence
Bacteria	7F1540R	5’-CAGAGTTTGATCCTGGCT-3’
Bacteria	16S rDNA	5’-AGGAGGTGATCCAGCCGCA-3’
Bacteria	27F1492R	5’-AGTTTGATCMTGGCTCAG-3’
Bacteria	16S rDNA	5’-GGTTACCTTGTTACGACTT-3’
Fungus	ITS1	5’-TCCGTAGGTGAACCTGCGG-3’
Fungus	ITS4	5’-TCCTCCGCTTATTGATATGC-3’
Fungus	NS1	5’-GTAGTCATATGCTTGTCTC-3’
Fungus	NS6	5’-GCATCACAGACCTGTTATTGCCTC-3’
PCNA		Forward: 5’-CCTGCTGGGATATTAGCTCCA-3’
PCNA		Reverse: 5’-CAGCGGTAGGTGTCGAAGC-3’
Rac		Forward: 5’-AAGGAGCCCCACGAGAAAAAT-3’
Rac		Reverse: 5’-ACCGAACTTGCATTGATTCCAG-3’
Rho		Forward: 5’-CTCGCTCAGTGCGAAGACAA-3’
Rho		Downstream: 5’-CATTCTCTGACGACATTTTCCCT-3’
Elongin C		Forward: 5’-AACCCGGACCCTAAGAAGCTA-3’
Elongin C		Reverse: 5’-TCTCCGCAAGAATGTCTACTGTA-3’
MSH6		Forward: 5’-CCAAGGCGAAGAACCTCAAC-3’
MSH6		Reverse: 5’-ACCAGGGGTAACCCTCCATC-3’
TRK		Forward: 5’-ACCCCGATTCCCCTAATAGAGG-3’
TRK		Reverse: 5’-ACCAGAACTCGGTAATCTGACT-3’
GAPDH		Forward: 5’-TCGTGGATCTGACGTGCCGCCTG-3’
GAPDH		Reverse: 5’-CACCACCCTGTTGCTGTAGCCGTAT-3’

PCNA: Proliferating cell nuclear antigen; MSH6: Melanocyte-stulating hormone-6; TRK: Tropomyosin receptor kinase; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.

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Citation: Lai Y, Xu JH, Chen YJ, Luo H, Lin Y, Yu YF, Chen QK. Enterocloster bolteae drives hyperglycemia-associated colorectal cancer cell proliferation via Rac/Rho-MSH6-Elongin C signaling pathway. World J Gastrointest Oncol 2026; 18(10): 119879
URL: https://www.wjgnet.com/1948-5204/full/v18/i10/119879.htm
DOI: https://dx.doi.org/10.4251/wjgo.119879

Lai Y, Xu JH, Chen YJ, Luo H, Lin Y, Yu YF, Chen QK. Enterocloster bolteae drives hyperglycemia-associated colorectal cancer cell proliferation via Rac/Rho-MSH6-Elongin C signaling pathway. World J Gastrointest Oncol 2026; 18(10): 119879 [DOI: 10.4251/wjgo.119879]

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