Colossal well-differentiated liposarcoma of the small bowel mesentery: A case report

Figure 4 Pathological examination results. Histopathological examination showed hematoxylin and eosin stains (× 40). Microscopic examination of the mesenteric mass showing variably sized lipoblasts with vacuolated cytoplasm, central hyperchromatic nuclei and nuclear scalloping. Histopathologic features of well-differentiated liposarcoma. A-F: Immunohistochemical stain is positive for the neoplastic cells. Positive: MDM2 (A), S-100 (B), P16 (C), Vim (D), Ki-67 (3%; E), and p53 (F); G and H: Immunohistochemical stain is negative [CK-pan (G) and EMA (H)]; I and J: Fluorescence in situ hybridization showed that MDM2 gene amplification is further confirmed (red signals represent MDM2; green signals represent chromosome 12 centromeres; magnification: × 400).