Clinicopathologic features of SMARCB1/INI1-deficient pancreatic undifferentiated rhabdoid carcinoma: A case report and review of literature

Figure 3 Representative hematoxylin and eosin staining. A: Low-power view showing a nodular lesion with adjacent spleen and pancreas. The spleen is located in the upper part of the image, while a small portion of pancreatic tissue is visible in the lower left corner. Foci of micropapillary carcinoma and undifferentiated carcinoma (UDC) demonstrate transitional areas between ductal adenocarcinoma and UDC, with metastatic deposits identified in a regional lymph node; B: A purplish-red appearance with a background of loose stroma, demonstrating a mixture of residual renal architecture and tumor infiltration. Preserved renal tubules and collecting ducts are visible on the right. At the same time, dense clusters of tumor cells with indistinct borders occupy the central and left regions, consistent with an invasive growth pattern. Focal necrosis is also observed; C: Section showing multiple rounds to oval glandular structures, representing moderately to well-differentiated ductal adenocarcinoma with micropapillary components. Tumor cells are unevenly distributed, and cellular density and heterogeneity vary across regions.