Multimodal clinical parameters-based immune status associated with the prognosis in patients with hepatocellular carcinoma

doi:10.4251/wjgo.v18.i1.112896

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jan 15, 2026; 18(1): 112896
Published online Jan 15, 2026. doi: 10.4251/wjgo.v18.i1.112896

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Figure 2 Evaluation of immunohistochemical markers in prognostic risk stratification for hepatocellular carcinoma. By analyzing the expression patterns of key immune checkpoints and biomarkers in the tumor microenvironment, the prognostic risks of HCC were classified into three categories: High risk, intermediate risk, and protective factors. PD-L1: Programmed death-ligand 1; PD-1: Programmed cell death protein 1; TIM-3: T-cell immunoglobulin and mucin-domain containing-3; MMP: Matrix metalloproteinase; DCP: Des-gamma-carboxy prothrombin; GP73: Golgi protein 73; AFP: Alpha-fetoprotein; AFP-L3: Alpha-fetoprotein L3 fraction; LAG-3: Lymphocyte-activation gene 3.

Citation: Zhang YZ, Tang YZ, He YX, Pan ST, Dai HC, Liu Y, Zhou HF. Multimodal clinical parameters-based immune status associated with the prognosis in patients with hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(1): 112896
URL: https://www.wjgnet.com/1948-5204/full/v18/i1/112896.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i1.112896

Zhang YZ, Tang YZ, He YX, Pan ST, Dai HC, Liu Y, Zhou HF. Multimodal clinical parameters-based immune status associated with the prognosis in patients with hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(1): 112896 [PMID: 41607766 DOI: 10.4251/wjgo.v18.i1.112896]

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