Multimodal clinical parameters-based immune status associated with the prognosis in patients with hepatocellular carcinoma

Table 4 Relationships between imaging features and prognosis of different imaging examinations in hepatocellular carcinoma

Imaging examination	Imaging features		Prognosis
CT	Tumor number	≤ 3	Good
		> 3	Poor
	Maximum diameter of the tumor	≤ 5 cm	Good
		> 5 cm	Poor
	Tumor envelope	Exist	Good
		Absence	Poor
	Irregular edge reinforcement	Absence	Good
		Exist	Poor
	Distribution of tumors across lobes	Absence	Good
		Exist	Poor
	Envelop invasion (arch-string ratio)	≤ 1	Good
		> 1	Poor
	Diaphragm invasion	Absence	Good
		Exist	Poor
	Cirrhosis	Absence	Good
		Exist	Poor
	The proportion of tumor convex	< 25%	Good
		≥ 25%	Poor
	Portal vein occlusion	Absence	Good
		Exist	Poor
MRI	Peritumoral enhancement	Absence	Good
		Exist	Poor
	Intratumoral necrosis	Absence	Good
		Exist	Poor
	Internal aneurysm	Absence	Good
		Exist	Poor
	Tumor edge	Smooth	Good
		Rag	Poor
	Multifocality	Absence	Good
		Exist	Poor
	Low density ring	Exist	Good
		Absence	Poor
Ultrasound	Tumor enhancement starts for a long time	Absence	Good
		Exist	Poor
	The arterial phase was highly enhanced	Absence	Good
		Exist	Poor
	The portal phase was low and enhanced	Absence	Good
		Exist	Poor
	The delay period is low and enhanced	Absence	Good
		Exist	Poor
DSA	The arrival time is reduced	No	Good
		Yes	Poor
	The peak time rises	No	Good
		Yes	Poor
	Increased filling rate	No	Good
		Yes	Poor
	The curve width is elevated	No	Good
		Yes	Poor
	The mean passage time was increased	No	Good
		Yes	Poor
Radiomics	First-order statistics	Different phases based on CT or MRI
	Texture features
	Wavelet decompositions

CT: Computed tomography; MRI: Magnetic resonance imaging; DSA: Digital subtraction angiography.