Muscle mass correlates with rocuronium distribution volume and guides dose optimization in obese colorectal cancer patients

Table 9 Skeletal muscle index-based individualized rocuronium dosing regimen

Patient category	Induction dose	Maintenance dose	Dosing interval (min)	Expected achievement rate (%)	Recommended monitoring frequency	Accumulation risk assessment
Sarcopenia	0.52 mg/kg SMM	0.22 mg/kg SMM	50-65	93.8	Every 30 min	Low risk
Non-sarcopenia	0.64 mg/kg SMM	0.16 mg/kg SMM	45-60	93.2	Every 45 min	Low risk

SMM: Skeletal muscle mass.