Muscle mass correlates with rocuronium distribution volume and guides dose optimization in obese colorectal cancer patients

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jan 15, 2026; 18(1): 112742
Published online Jan 15, 2026. doi: 10.4251/wjgo.v18.i1.112742

Table 6 Structural model comparison

Model	Number of parameters	OFV	AIC	BIC	△OFV	P value	Parameter estimation stability
One-compartment	6	2847.3	2859.3	2877.8	-	-	Good
Two-compartment	8	2764.8	2780.8	2805.6	-82.5	< 0.001	Good
Three-compartment	10	2761.2	2781.2	2812.4	-3.6	0.165	Poor (RSE > 30%)

OFV: Objective function value; AIC: Akaike information criterion; BIC: Bayesian information criterion; RSE: Relative standard error.

Citation: Li ZW, Liu Z, Liu SQ. Muscle mass correlates with rocuronium distribution volume and guides dose optimization in obese colorectal cancer patients. World J Gastrointest Oncol 2026; 18(1): 112742
URL: https://www.wjgnet.com/1948-5204/full/v18/i1/112742.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i1.112742

Li ZW, Liu Z, Liu SQ. Muscle mass correlates with rocuronium distribution volume and guides dose optimization in obese colorectal cancer patients. World J Gastrointest Oncol 2026; 18(1): 112742 [PMID: 41607758 DOI: 10.4251/wjgo.v18.i1.112742]

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