Sonazoid-contrast-enhanced ultrasound for the histological diagnosis of hepatocellular carcinoma

doi:10.4251/wjgo.v18.i1.111144

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Oncol. Jan 15, 2026; 18(1): 111144
Published online Jan 15, 2026. doi: 10.4251/wjgo.v18.i1.111144

Table 2 Diagnostic performance of variables

Variable	Cut-off value	Sensitivity (%)	Specificity (%)	AUC
AFP (ng/mL)	97.69	57.4	83.6	0.739
Tumor size (cm)	4.65	53.9	70.8	0.610
EIAV (dB)	56.384	40.2	78.1	0.590
ID (dB)	9.184	80.4	74.5	0.815
IR	1.215	82.4	86.9	0.877

AUC: Area under the receiver operating characteristic curve; AFP: Alpha-fetoprotein; EIAV: Enhancement intensity; ID: Intensity difference; IR: Intensity ratio.

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Citation: Liu RB, Xin JY, Huang Z, Li KY. Sonazoid-contrast-enhanced ultrasound for the histological diagnosis of hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(1): 111144
URL: https://www.wjgnet.com/1948-5204/full/v18/i1/111144.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i1.111144

Liu RB, Xin JY, Huang Z, Li KY. Sonazoid-contrast-enhanced ultrasound for the histological diagnosis of hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(1): 111144 [PMID: 41607751 DOI: 10.4251/wjgo.v18.i1.111144]

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