Serum gastrin and Helicobacter pylori infection correlate with tumor aggressiveness and prognosis in gastric cancer

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Sep 15, 2025; 17(9): 110981
Published online Sep 15, 2025. doi: 10.4251/wjgo.v17.i9.110981

Table 2 Relationship between gastrin and pathologic features

	Gastrin-negative	Gastrin-positive	χ²	P value
n	90	136
TNM staging			9.637	0.002
I-II	51	50
III-IV	39	86
Lymphatic metastasis			5.899	0.015
No	69	84
Yes	21	52
Degrees of differentiation			5.265	0.022
Medium-high differentiation	67	82
Low differentiation	23	54

TNM: Tumor-nodes-metastasis.

Citation: Huang JW, Lin C, Lu CJ, Wang HS, Zou DD. Serum gastrin and Helicobacter pylori infection correlate with tumor aggressiveness and prognosis in gastric cancer. World J Gastrointest Oncol 2025; 17(9): 110981
URL: https://www.wjgnet.com/1948-5204/full/v17/i9/110981.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i9.110981

Huang JW, Lin C, Lu CJ, Wang HS, Zou DD. Serum gastrin and Helicobacter pylori infection correlate with tumor aggressiveness and prognosis in gastric cancer. World J Gastrointest Oncol 2025; 17(9): 110981 [PMID: 40977652 DOI: 10.4251/wjgo.v17.i9.110981]

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