Transcription factor 3 enhances hepatocellular carcinoma metastasis by upregulating matrix metalloproteinase-11

doi:10.4251/wjgo.v17.i9.110527

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Sep 15, 2025; 17(9): 110527
Published online Sep 15, 2025. doi: 10.4251/wjgo.v17.i9.110527

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Figure 5 Transcription factor 3 expression levels are positively correlated with matrix metalloproteinase-11 Levels in hepatocellular carcinoma. A: Heatmap of transcription factor 3 (TCF3) and matrix metalloproteinase-11 (MMP11) mRNA expression in liver hepatocellular carcinoma (HCC) cases obtained from The Cancer Genome Atlas; B: Correlation between the expression of TCF3 and MMP11 at mRNA levels extracted from cbioportal database; C: Demonstrative immunohistochemical staining images for TCF3 and MMP11 in human HCC tissues. Scale bars: 50 μm (high magnification) and 200 μm (low magnification). HCC: Hepatocellular carcinoma; MMP11: Matrix metalloproteinase-11; TCF3: Transcription factor 3.

Citation: Tian HP, Wu TH, Zhang GJ, Li SJ. Transcription factor 3 enhances hepatocellular carcinoma metastasis by upregulating matrix metalloproteinase-11. World J Gastrointest Oncol 2025; 17(9): 110527
URL: https://www.wjgnet.com/1948-5204/full/v17/i9/110527.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i9.110527

Tian HP, Wu TH, Zhang GJ, Li SJ. Transcription factor 3 enhances hepatocellular carcinoma metastasis by upregulating matrix metalloproteinase-11. World J Gastrointest Oncol 2025; 17(9): 110527 [PMID: 40977645 DOI: 10.4251/wjgo.v17.i9.110527]

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