Rapamycin suppresses small bowel adenocarcinoma HUTU 80 cells proliferation by inhibiting hypoxia-inducible factor-1α mediated metabolic reprogramming

Figure 3 Effects of rapamycin on cell cycle of HUTU 80 cells. A: Flow cytometry was used to assess cell cycle changes; B: Statistical map of cell cycle distribution; C: Detection of protein expression of cell cycle proteins by western blotting; D: Statistical graph of protein expression. Data are presented as the mean ± SD (n = 3). ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. PI-A: Propidium iodide-area; RAPA: Rapamycin; NS: No significance; CDK2: Cyclin-dependent kinases 2.