Rapamycin suppresses small bowel adenocarcinoma HUTU 80 cells proliferation by inhibiting hypoxia-inducible factor-1α mediated metabolic reprogramming

Figure 2 Effects of rapamycin on migration and invasion of HUTU 80 cells. A: Detection of the effect of rapamycin (RAPA) on cell migration ability through a wound healing assay; B: Assessment of the influence of RAPA on cell invasion capabilities using Transwell assay; C: Statistical chart of the cell migration ratio; D: Statistical chart of cell invasion ability; E: Quantitative polymerase chain reaction was used to evaluate the messenger RNA expression level of MMP2. Data are presented as the mean ± SD (n = 3). ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. MMP: Matrix metalloproteinase; RAPA: Rapamycin.