Methionyl-tRNA synthetase 1 participates in hepatocellular carcinoma and its regulated gene profile possesses potent prognostic ability

doi:10.4251/wjgo.v17.i9.109127

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Sep 15, 2025; 17(9): 109127
Published online Sep 15, 2025. doi: 10.4251/wjgo.v17.i9.109127

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Figure 8 Identification of different MRPS groups differentially expressed genes and functional enrichment analysis. A: Volcano plots showing 808 differentially expressed genes (DEGs) between different MRPS groups; B: Heatmap illustrating the expression patterns of the 808 DEGs between high and low MRPS patients; C: Gene Ontology enrichment analysis displaying the biological processes, cell components, and molecular functions associated with MARS1-related genes; D: Kyoto Encyclopedia of Genes and Genomes pathways analysis highlighting the pathways enriched in MARS1-related genes, including complement and coagulation cascades, cell cycle, xenobiotic metabolism by cytochrome P450, and bile secretion.

Citation: Bu HY, Huang H, Li J, Huang ZB, Huang Y, Huang YK, Wang AM, Wu L, Yuan J, Wang RJ, Lu M, Yu SM, Yi PP, Chen YY, Jiang YP, Hu XW. Methionyl-tRNA synthetase 1 participates in hepatocellular carcinoma and its regulated gene profile possesses potent prognostic ability. World J Gastrointest Oncol 2025; 17(9): 109127
URL: https://www.wjgnet.com/1948-5204/full/v17/i9/109127.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i9.109127

Bu HY, Huang H, Li J, Huang ZB, Huang Y, Huang YK, Wang AM, Wu L, Yuan J, Wang RJ, Lu M, Yu SM, Yi PP, Chen YY, Jiang YP, Hu XW. Methionyl-tRNA synthetase 1 participates in hepatocellular carcinoma and its regulated gene profile possesses potent prognostic ability. World J Gastrointest Oncol 2025; 17(9): 109127 [PMID: 41262077 DOI: 10.4251/wjgo.v17.i9.109127]

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