Downregulation of uncoupling protein 1 by hypermethylation in gastric cancer activates Rap1 signaling

doi:10.4251/wjgo.v17.i9.108760

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Sep 15, 2025; 17(9): 108760
Published online Sep 15, 2025. doi: 10.4251/wjgo.v17.i9.108760

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Figure 1 Uncoupling protein 1 was differentially expressed in gastric cancer formalin-fixed paraffin-embedded tissues as revealed by immunohistochemistry staining. A: Uncoupling protein 1 was positively expressed in normal gastric tissues; B-D: It was negatively (B) expressed in some of gastric cancer (GC) tissues (76 out of 211), and moderately (C) and strongly (D) expressed in some of GC tissues (135 out of 211). Image magnification: 200 ×.

Citation: Chen YJ, Peng C, Wang LW, Chai JX, Wang JD, He QB. Downregulation of uncoupling protein 1 by hypermethylation in gastric cancer activates Rap1 signaling. World J Gastrointest Oncol 2025; 17(9): 108760
URL: https://www.wjgnet.com/1948-5204/full/v17/i9/108760.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i9.108760

Chen YJ, Peng C, Wang LW, Chai JX, Wang JD, He QB. Downregulation of uncoupling protein 1 by hypermethylation in gastric cancer activates Rap1 signaling. World J Gastrointest Oncol 2025; 17(9): 108760 [PMID: 40977672 DOI: 10.4251/wjgo.v17.i9.108760]

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