Downregulation of uncoupling protein 1 by hypermethylation in gastric cancer activates Rap1 signaling

Table 3 Multivariate logistic regression analysis of the association between uncoupling protein 1 methylation and clinicopathological characteristics in patients with gastric cancer

Clinicopathological characteristics	OR	95%CI	P value
Sex (male vs female)	1.958	0.958-4.001	0.065
Age (≥ 65 years vs < 65 years)	0.870	0.467-1.622	0.662
Depth of invasion (T3/T4 vs T1/T2)	1.677	0.592-4.751	0.330
Differentiation (well & moderate vs poor)	0.446	0.227-0.880	0.020a
Lymph mode metastasis (yes vs no)	1.057	0.455-2.455	0.898
TNM Stage (III and IV vs I/II)	0.233	0.115-0.469	< 0.001b

^aP < 0.05.

^bP < 0.001.

OR: Odds ratio; 95%CI: 95% confidence interval.