DEAD/H-box RNA helicase 10 promotes pancreatic cancer cell proliferation via ribonucleotide reductase M2

Figure 8 Clinical relevance of DEAD/H-box RNA helicase 10 and predictor proteins in TCGA data and experimental validation. A: ITGA2, LIG1, RRM2, CDK6 are positively correlated with DEAD/H-box RNA helicase 10 (DDX10) expression; B: Western blotting verified the protein expression of 6 proteins in NC and shDDX10 groups; C: QPCR detection of mRNA expression of DDX10 in grouped cells; D: QPCR detection of mRNA expression of RRM2 in grouped cells; E: Functional rescue assay of shDDX10 with RRM2 overexpression detected by cell counting kit-8. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001; NS: No significance; DDX10: DEAD/H-box RNA helicase 10.