DEAD/H-box RNA helicase 10 promotes pancreatic cancer cell proliferation via ribonucleotide reductase M2

Figure 4 Knockdown of EAD/H-box RNA helicase 10 inhibits migration and invasion of pancreatic cancer cells. A and B: Representative images of wound healing by DEAD/H-box RNA helicase 10 (DDX10) knockdown (shRNA) and control (NC) cells were photographed at 0 hour and 24 hours after scraping; C: Cell migration was measured by transwell assays; D: Transwell invasion assays using DDX10-knockdown AsPC-1 and PANC-1 cells; Number of migrated cells was exhibited as the mean ± SD of three randomly chosen visual fields from three independent experiments. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001; NS: No significance; PC: Pancreatic cancer.