Efficacy of adjuvant chemotherapy in stage II colon cancer patients with twelve or more lymph nodes retrieve

doi:10.4251/wjgo.v17.i9.108470

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Oncol. Sep 15, 2025; 17(9): 108470
Published online Sep 15, 2025. doi: 10.4251/wjgo.v17.i9.108470

Table 3 The clinicopathological characteristics of the Surveillance, Epidemiology, and End Results and Chinese cohorts before and after propensity score matching, n (%)

Characteristics	Before PSM¹			After PSM¹			Before PSM²			After PSM²
Characteristics	No	Yes	P value	No	Yes	P value	No	Yes	P value	No	Yes	P value
Total	28228	4514		4204	4204		1429	1724		1163	1163
ELN, mean ± SD	22.18 ± 9.92	23.36 ± 10.69	< 0.001	22.52 ± 10.15	23.40 ± 10.72	< 0.001	19.98 ± 8.28	19.79 ± 7.59	0.502	19.68 ± 7.83	19.97 ± 7.64	0.368
Size, mean ± SD	5.55 ± 3.50	6.13 ± 3.66	< 0.001	6.08 ± 3.88	6.13 ± 3.52	0.568	5.21 ± 2.15	5.46 ± 2.23	0.002	5.23 ± 2.15	5.28 ± 2.08	0.58
Age			< 0.001			0.658			< 0.001			0.834
20-64	7144 (25.3)	2769 (61.3)		2438 (58.0)	2459 (58.5)		681 (47.7)	1203 (69.8)		666 (57.3)	660 (56.7)
Sex			< 0.001			0.169			0.097			0.474
Male	13274 (47.0)	2312 (51.2)		2128 (50.6)	2192 (52.1)		796 (55.7)	1012 (58.7)		673 (57.9)	691 (59.4)
Grade			< 0.001			0.96			1			0.9
Grade 3/4	5395 (19.1)	1126 (24.9)		1025 (24.4)	1028 (24.5)		179 (12.5)	216 (12.5)		145 (12.5)	142 (12.2)
Histology			0.255			0.436			0.002			0.164
Adenocarcinoma	24161 (85.6)	3835 (85.0)		3610 (85.9)	3591 (85.4)		1238 (86.6)	1445 (83.8)		1011 (86.9)	981 (84.4)
Mucinous adenocarcinoma	3627 (12.8)	595 (13.2)		531 (12.6)	535 (12.7)		164 (11.5)	261 (15.1)		138 (11.9)	169 (14.5)
Others	440 (1.6)	84 (1.9)		63 (1.5)	78 (1.9)		27 (1.9)	18 (1.0)		14 (1.2)	13 (1.1)
T stage			< 0.001			0.641			0.27			0.525
T4	3167 (11.2)	1655 (36.7)		1369 (32.6)	1348 (32.1)		402 (28.1)	517 (30.0)		336 (28.9)	351 (30.2)

¹Surveillance, Epidemiology, and End Results database.

²Chinese registry.

PSM: Propensity score matching; ELN: Examined lymph node.

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Citation: Huo Y, Zhang YY, Jiao S, Bai ZY, Bai WQ, Zhou HT, Guan X. Efficacy of adjuvant chemotherapy in stage II colon cancer patients with twelve or more lymph nodes retrieve. World J Gastrointest Oncol 2025; 17(9): 108470
URL: https://www.wjgnet.com/1948-5204/full/v17/i9/108470.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i9.108470

Huo Y, Zhang YY, Jiao S, Bai ZY, Bai WQ, Zhou HT, Guan X. Efficacy of adjuvant chemotherapy in stage II colon cancer patients with twelve or more lymph nodes retrieve. World J Gastrointest Oncol 2025; 17(9): 108470 [PMID: 40977670 DOI: 10.4251/wjgo.v17.i9.108470]

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