Efficacy of adjuvant chemotherapy in stage II colon cancer patients with twelve or more lymph nodes retrieve

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Oncol. Sep 15, 2025; 17(9): 108470
Published online Sep 15, 2025. doi: 10.4251/wjgo.v17.i9.108470

Table 1 The clinicopathological characteristics of the Surveillance, Epidemiology, and End Results cohort and the Chinese cohort, n (%)

Characteristics	SEER database	Chinese registry
Total	32742	3153
Examined lymph node, median (IQR)	20.00 (15.00, 26.00)	18.00 (15.00, 22.00)
Chemotherapy
No	28228 (86.2)	1429 (45.3)
Yes	4514 (13.8)	1724 (54.7)
Size, median (IQR)	5.00 (3.80, 7.00)	5.00 (4.00, 6.50)
Age
≥ 65	22829 (69.7)	1269 (40.2)
20-64	9913 (30.3)	1884 (59.8)
Sex
Female	17156 (52.4)	1345 (42.7)
Male	15586 (47.6)	1808 (57.3)
Grade
Grade 1/2	26221 (80.1)	2758 (87.5)
Grade 3/4	6521 (19.9)	395 (12.5)
Histology
Adenocarcinoma	27996 (85.5)	2683 (85.1)
Mucinous adenocarcinoma	4222 (12.9)	425 (13.5)
Others	524 (1.6)	45 (1.4)
T stage
T3	27920 (85.3)	2234(70.9)
T4	4822 (14.7)	919 (29.1)

SEER: Surveillance, Epidemiology, and End Results; IQR: Interquartile range.

Citation: Huo Y, Zhang YY, Jiao S, Bai ZY, Bai WQ, Zhou HT, Guan X. Efficacy of adjuvant chemotherapy in stage II colon cancer patients with twelve or more lymph nodes retrieve. World J Gastrointest Oncol 2025; 17(9): 108470
URL: https://www.wjgnet.com/1948-5204/full/v17/i9/108470.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i9.108470

Huo Y, Zhang YY, Jiao S, Bai ZY, Bai WQ, Zhou HT, Guan X. Efficacy of adjuvant chemotherapy in stage II colon cancer patients with twelve or more lymph nodes retrieve. World J Gastrointest Oncol 2025; 17(9): 108470 [PMID: 40977670 DOI: 10.4251/wjgo.v17.i9.108470]

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