Relationship between uric acid and colon cancer risk: Dose-response analysis and mechanisms

doi:10.4251/wjgo.v17.i9.107651

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Sep 15, 2025; 17(9): 107651
Published online Sep 15, 2025. doi: 10.4251/wjgo.v17.i9.107651

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Figure 4 Effect of uric acid on reactive oxygen species in HCT-116 cells. A: Reactive oxygen species (ROS) expression in HCT-116 cells before uric acid intervention; B: ROS expression in HCT-116 cells after uric acid intervention for 48 hours; C: Comparison of different groups of ROS expression. ^aP < 0.05 vs 0 mg/dL group or between groups; NS: Not statistically significant, compared with the 0 mg/dL group. ROS: Reactive oxygen species; DAPI: 4'-6-diamidino-2-phenylindole.

Citation: Sun TF, Fan KX, Luo YX, Song J, Han ZX, Zhang XL. Relationship between uric acid and colon cancer risk: Dose-response analysis and mechanisms. World J Gastrointest Oncol 2025; 17(9): 107651
URL: https://www.wjgnet.com/1948-5204/full/v17/i9/107651.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i9.107651

Sun TF, Fan KX, Luo YX, Song J, Han ZX, Zhang XL. Relationship between uric acid and colon cancer risk: Dose-response analysis and mechanisms. World J Gastrointest Oncol 2025; 17(9): 107651 [PMID: 40977646 DOI: 10.4251/wjgo.v17.i9.107651]

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