Correlation between KAT6A and PD-L1 expression and role of KAT6A in colorectal cancer

doi:10.4251/wjgo.v17.i9.105937

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Sep 15, 2025; 17(9): 105937
Published online Sep 15, 2025. doi: 10.4251/wjgo.v17.i9.105937

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Figure 3 KAT6A-mediated H3K23pr activates PD-L1 expression in colorectal cancer cells. SW480 and SW620 cells were transfected with KAT6A siRNAs. A: The levels of H3K23pr were detected by Western blotting assay; B: The enrichment of H3K23pr on PD-L1 promoter was analyzed by ChIP-PCR; C: The mRNA expression of PD-L1 was measured by quantitative PCR. ^bP < 0.01.

Citation: Zhou ZD, Zhao JP, Zheng SC, Wang TT. Correlation between KAT6A and PD-L1 expression and role of KAT6A in colorectal cancer. World J Gastrointest Oncol 2025; 17(9): 105937
URL: https://www.wjgnet.com/1948-5204/full/v17/i9/105937.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i9.105937

Zhou ZD, Zhao JP, Zheng SC, Wang TT. Correlation between KAT6A and PD-L1 expression and role of KAT6A in colorectal cancer. World J Gastrointest Oncol 2025; 17(9): 105937 [PMID: 40977654 DOI: 10.4251/wjgo.v17.i9.105937]

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