Bone marrow metastasis of gastric signet ring cell carcinoma complicated by thrombotic microangiopathy: A case report

doi:10.4251/wjgo.v17.i8.109424

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

World J Gastrointest Oncol. Aug 15, 2025; 17(8): 109424
Published online Aug 15, 2025. doi: 10.4251/wjgo.v17.i8.109424

Table 2 Laboratory data during hospitalization

Parameter	Day 1	Day 7	Day 21	Reference range
Hb (g/dL)	64	37	21	130-175
PLT (10⁹/L)	19	20	23	125-350
WBC (10⁹/L)	5.8	3.5	7.4	3.5-9.5
RBC (10¹²/L)	2.19	1.17	0.60	4.4-5.8
RET%	10.63	14.76	---	0.5-1.5%
TBil (μmol/ L)	121.1	58.3	79.3	3.42-20.52
IBIL (μmol/L)	94.3	46.5	61.1	2-18
DBiL (μmol/L)	26.8	11.8	18.2	0.0-6.84
LDH (U/L)	1040	2226	1254	120-250
FIB (g/L)	0.6	1.35	0.69	2-4
PT (second)	33.4	20.3	24.8	11.0-14.5
Scr (μmol/L)	46	25	25	57-110
ADAMTS-13 activity	-	-	100	0-100%
ADAMTS-13 inhibitor	-	-	Negative	-/+

Hb: Hemoglobin; PLT: Platelet; RBC: Red blood cell; WBC: White blood cell; RET%: Reticulocyte percentage; TBil: Total bilirubin; DBiL: Direct bilirubin; IBIL: Indirect bilirubin; LDH: Lactate dehydrogenase; PT: Prothrombin time; FIB: Fibrinogen; Scr: Serum creatinine; ADAMTS-13: A disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13, involved in regulating blood clotting.

Citation: Sun W, Chen XC, Wang H, Chang WY, He Y, Lin ZH, Jia H, Zhang XM, Liu H. Bone marrow metastasis of gastric signet ring cell carcinoma complicated by thrombotic microangiopathy: A case report. World J Gastrointest Oncol 2025; 17(8): 109424
URL: https://www.wjgnet.com/1948-5204/full/v17/i8/109424.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i8.109424