Exploration of the association between SF3B4 and HMGB1 expression and the clinicopathological features and prognosis of gastric cancer

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Aug 15, 2025 (publication date) through Sep 1, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Oncol. Aug 15, 2025; 17(8): 109120
Published online Aug 15, 2025. doi: 10.4251/wjgo.v17.i8.109120

Table 6 Variable assignment

Independent variable	Assignment method
Independent variable	0, survived	1, deceased
SF3B4	< 1.45	≥ 1.45
HMGB1	< 0.93	≥ 0.93
Tumor differentiation	Moderate to high differentiation	Poor differentiation
Maximum tumor diameter, cm	< 5	≥ 5
Tumor invasion depth	T1-T2	T3-T4
Lymph node metastasis	No	Yes
cTNM stage	I-II	III-IV

cTNM: Clinical tumor-node-metastasis.

Citation: Shou MY, Liu YQ, Shu YQ. Exploration of the association between SF3B4 and HMGB1 expression and the clinicopathological features and prognosis of gastric cancer. World J Gastrointest Oncol 2025; 17(8): 109120
URL: https://www.wjgnet.com/1948-5204/full/v17/i8/109120.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i8.109120