Exploration of the association between SF3B4 and HMGB1 expression and the clinicopathological features and prognosis of gastric cancer

doi:10.4251/wjgo.v17.i8.109120

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Aug 15, 2025; 17(8): 109120
Published online Aug 15, 2025. doi: 10.4251/wjgo.v17.i8.109120

Table 5 Analysis of the predictive value of splicing factor 3b subunit 4 and high mobility group box 1 expression in tissues for poor prognosis of gastric cancer at 1 year

Index	Optimal cutoff value	AUC	95%CI	P value	Sensitivity, %	Specificity, %
SF3B4	1.65	0.776	0.692-0.835	< 0.001	78.35	79.18
HMGB1	0.92	0.757	0.661-0.813	< 0.001	80.26	78.74
Combined	-	0.914	0.819-0.947	< 0.001	90.17	91.43

SF3B4: Splicing factor 3b subunit 4; HMGB1: High mobility group box 1; AUC: Area under the curve; CI: Confidence interval.

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Citation: Shou MY, Liu YQ, Shu YQ. Exploration of the association between SF3B4 and HMGB1 expression and the clinicopathological features and prognosis of gastric cancer. World J Gastrointest Oncol 2025; 17(8): 109120
URL: https://www.wjgnet.com/1948-5204/full/v17/i8/109120.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i8.109120

Shou MY, Liu YQ, Shu YQ. Exploration of the association between SF3B4 and HMGB1 expression and the clinicopathological features and prognosis of gastric cancer. World J Gastrointest Oncol 2025; 17(8): 109120 [PMID: 40837768 DOI: 10.4251/wjgo.v17.i8.109120]

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