Noninvasive prediction of microsatellite instability in stage II/III rectal cancer using dynamic contrast-enhanced magnetic resonance imaging radiomics

Table 4 First-order statistical features and signal intensity characteristics, mean ± SD

Feature	MSI-H (n = 30)	MSS/MSI-L (n = 90)	P value
Signal intensity variance	3642 ± 782	2815 ± 645	0.007
Kurtosis	4.86 ± 1.12	3.53 ± 0.98	0.005
Skewness	0.89 ± 0.28	0.42 ± 0.19	0.003
Mean signal intensity	785.3 ± 134.2	693.6 ± 128.7	0.009
Peak enhancement (%)	43.7 ± 8.9	35.2 ± 7.4	0.006
Minimum signal intensity	220.5 ± 45.6	250.3 ± 48.9	0.021
Maximum signal intensity	1350.7 ± 210.4	1200.3 ± 180.5	0.013
Signal intensity range	1130.2 ± 190.8	950.0 ± 160.2	0.004
Median signal intensity	750.4 ± 120.3	680.2 ± 110.5	0.011
Standard deviation	300.5 ± 50.2	250.3 ± 45.6	0.008

MSI-H: Microsatellite instability-high; MSS: Microsatellite stability; MSI-L: Microsatellite instability-low.