Noninvasive prediction of microsatellite instability in stage II/III rectal cancer using dynamic contrast-enhanced magnetic resonance imaging radiomics

Table 3 Morphological and shape-based radiomics features, mean ± SD

Feature	MSI-H (n = 30)	MSS/MSI-L (n = 90)	P value
Surface-to-volume ratio	0.72 ± 0.14	0.58 ± 0.11	0.008
Sphericity	0.68 ± 0.09	0.79 ± 0.08	0.006
Fractal dimension	1.28 ± 0.07	1.19 ± 0.06	0.009
Maximum 3D diameter (cm)	5.8 ± 1.2	4.9 ± 1.0	0.011
Border irregularity	0.85 ± 0.12	0.68 ± 0.10	0.004
Major axis length (cm)	6.2 ± 1.3	5.3 ± 1.1	0.012
Minor axis length (cm)	3.8 ± 0.9	4.2 ± 0.8	0.035
Least axis length (cm)	2.9 ± 0.7	3.5 ± 0.6	0.021
Surface area (cm2)	125.4 ± 25.6	108.7 ± 20.3	0.007
Flatness	0.45 ± 0.08	0.58 ± 0.07	0.002
Elongation	0.72 ± 0.10	0.64 ± 0.09	0.015

MSI-H: Microsatellite instability-high; MSS: Microsatellite stability; MSI-L: Microsatellite instability-low.