Pathological complete response in advanced intrahepatic cholangiocarcinoma was achieved through tri-modal therapy: A case report and review of literature

Figure 1 Serial contrast-enhanced computed tomography imaging during the treatment course. A: Pre-chemotherapy baseline computed tomography (CT) showing a 13-cm hypodense mass (blue arrow) with heterogeneous enhancement in the left hepatic lobe, exhibiting mild to moderate peripheral enhancement and left portal branch encasement (orange arrow); B: Follow-up CT after 3 cycles of combined therapy demonstrating a significant reduction in tumor diameter to 6.5 cm (blue arrow), with attenuated enhancement compared to baseline and alleviated left portal branch involvement (orange arrow); C: Post-resection CT at 24-month follow-up revealing no evidence of tumor recurrence; D: Post-resection CT at 29-month follow-up confirming the absence of tumor recurrence.