BTNL9 exerts anti-cancer effects by inhibiting CDC20 to induce G2/M arrest in pancreatic cancer

Figure 3 Effect of BTNL9 expression on pancreatic cancer cell cycle. A: Flow cytometry detected BTNL9 overexpressed cells arrested at G2/M phase; B: Xenograft tumor models showed decreased tumorigenic ability of BTNL9-overexpressing cells; C: Immunohistochemistry results of xenograft tumor tissue; D and E: Differentially expressed genes detected by RNA sequencing; F: BTNL9 overexpression showed significant enrichment of cell cycle signaling pathway; G: Expression of cell cycle related genes in two groups of cells. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. HE: Hematoxylin and eosin.