SAC3 domain containing 1 intervention in energy metabolism reprogramming assists in the progression of hepatocellular carcinoma

Figure 7 In vivo, SAC3 domain containing 1 significantly promotes the progression of hepatocellular carcinoma. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. A: Xenograft tumor of MHCC-97H SAC3 domain containing 1 overexpression and MHCC-97H control (Ctrl) cells and hematoxylin and eosin staining, bar = 50 μm; B: Statistical analysis of xenograft tumor volume and tumor weight; C and D: Immunohistochemistry detection and statistical analysis of the expression and positive rates of SAC3 domain containing 1, β-Catenin, c-Myc, glucose transporter 1, hexokinase 2, pyruvate kinase M2 and lactate dehydrogenase A, bar = 50 μm. OE: Over expression; NS: No significance; SAC3D1: SAC3 domain containing 1;GLUT1: Glucose transporter 1; HK2: Hexokinase 2; PKM2: Pyruvate kinase M2; LDHA: Lactate dehydrogenase A.