SAC3 domain containing 1 intervention in energy metabolism reprogramming assists in the progression of hepatocellular carcinoma

Figure 1 SAC3 domain containing 1 is upregulated in liver hepatocellular carcinoma and is associated with tumor grade and disease prognosis. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. A: Analysis of SAC3 domain containing 1 (SAC3D1) expression across different cancers using UALCAN database; B: Analysis of SAC3D1 expression in liver hepatocellular carcinoma and adjacent tissues using gene expression profiling interactive analysis; C: Correlation between high and low SAC3D1 expression and overall survival and progression-free survival in liver hepatocellular carcinoma patients, as analyzed by gene expression profiling interactive analysis; D: Correlation between SAC3D1 transcription levels and tumor stages; E: Correlation between SAC3D1 transcription levels and tumor grades; F: Correlation between SAC3D1 transcription levels and lymph node metastasis; G: Correlation between SAC3D1 transcription levels and gender; H: Correlation between SAC3D1 transcription levels and age. SAC3D1: SAC3 domain containing 1; LIHC: Liver hepatocellular carcinoma; TCGA: The Cancer Genome Atlas; NS: No significance.