Neutrophil extracellular traps predict sensitivity to neoadjuvant chemotherapy combined with immunotherapy in locally advanced gastric cancer

Figure 2 Evaluation of pre-neoadjuvant chemotherapy combined with immunotherapy and post-neoadjuvant chemotherapy combined with immunotherapy neutrophil extracellular traps in association with response to neoadjuvant chemotherapy combined with immunotherapy in locally advanced gastric cancer patients. A and B: Pre-neoadjuvant chemotherapy combined with immunotherapy (NACI) neutrophil extracellular trap (NETs) and post-NACI NETs according to response to NETs in locally advanced gastric cancer patients treated with NACI; C-G: Differences between pre-NACI NETs and post-NACI NETs between NET-treated responder, nonresponder, pathological complete response (pCR) and non-pCR groups. The plotted values encompass the range from minimum to maximum, with the inclusion of the median. NET: Neutrophil extracellular trap; NACI: Neoadjuvant chemotherapy combined with immunotherapy; pCR: Pathological complete response.