Correlation of serum cytokine-induced neutrophil chemoattractant levels with Helicobacter pylori infection and disease severity in gastric cancer patients

Table 3 Serum cytokine-induced neutrophil chemoattractant levels in patients with gastric cancer with or without concurrent malignancies, n (%)

Characteristic	Concurrent malignancies (n = 32)	No concurrent malignancies (n = 226)	P value
CINC (pg/mL)	395.2 ± 142.6	250.1 ± 110.3	< 0.001
H. pylori			0.005
H. pylori-positive	24 (75)	114 (50.44)
H. pylori-negative	8 (25)	112 (49.56)
Age (years)	62.4 ± 11.7	59.9 ± 10.5	0.214
Male gender	18 (56.3)	76 (33.6)	0.058
TNM stage			0.064
Stage I	8 (3.5)	2 (6.3)
Stage II	6 (18.8)	26 (11.5)
Stage III	10 (31.3)	44 (19.5)
Stage IV	14 (43.8)	148 (65.5)
Smoking history			0.179
Never	4 (12.5)	38 (16.9)
Former	6 (18.8)	22 (9.7)
Current	22 (68.8)	166 (73.5)
Alcohol consumption			0.165
Never	8 (25.0)	42 (18.6)
Former	3 (9.4)	14 (6.2)
Current	21 (65.6)	170 (75.2)
Family history of cancer			0.031
Yes	6 (18.8)	16 (7.1)
No	26 (81.3)	210 (92.9)
Previous gastric surgery			0.162
Yes	2 (6.3)	6 (2.7)
No	30 (93.8)	220 (97.3)

BMI: Body mass index; H. pylori: Helicobacter pylori; CINC: Cytokine-induced neutrophil chemoattractant.