Predictive value of a nomogram model for treatment response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Table 3 Logistic regression analysis of factors associated with poor response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

Factors	β	SE	Wald	OR	95%CI for OR	P value
Elevated CA19-9	0.185	0.088	1.828	1.149	0.871-1.271	0.271
Elevated TNF-α	0.191	0.08	2.39	1.142	0.864-1.261	0.133
Larger tumor diameter	0.367	0.112	2.582	1.312	0.905-1.392	0.101
Tumor poor differentiation	0.341	0.119	2.843	1.372	0.798-1.471	0.085
TNM/T stage 4	0.441	0.121	2.944	1.419	0.973-1.497	0.078
Lymph node metastasis	0.454	0.092	3.211	1.491	0.982-1.539	0.072
Elevated CEA	0.745	0.274	6.315	2.37	1.263-3.921	0.016
Elevated IL-6	0.926	0.296	7.41	2.666	1.507-4.305	0.012
Elevated CRP	0.887	0.252	7.819	2.571	1.576-4.108	0.009

OR: Odds ratio; CI: Confidence interval; CRP: C-reactive protein; IL-6: Interleukin-6; CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9; TNF-α: Tumor necrosis factor-alpha.