Noninvasive prediction of Ki-67 expression in pancreatic cancer via contrast-enhanced ultrasound quantitative parameters: A diagnostic model study

Table 5 Comparison of contrast-enhanced ultrasound quantitative parameters across tumors with different differentiation degrees, median (interquartile range)

	Well differentiated	Moderately differentiated	Poorly differentiated	Z value	P value	r value	P’ value
mTT	57.7 (49.42 to 74.12)	77.88 (41.81 to 88.58)	78.40 (64.33 to 100.52)	6.037	0.049a	-0.244	0.075
Rs50	9.31 (7.63 to 10.73)	10.59 (5.28 to 13.78)	10.30 (6.84 to 12.81)	0.367	0.832	-0.095	0.491
IMAX	54.30 (43.41 to 72.76)	54.37 (40.84 to 74.12)	58.56 (49.43 to 88.76)	0.687	0.709	-0.144	0.295
RT	12.34 (9.80 to 14.86)	12.67 (11.61 to 14.80)	11.84 (10.07 to 13.74)	0.687	0.709	0.084	0.084
WinAUC	408.93 (241.28 to 1082.16)	364.44 (155.50 to 850.82)	296.42 (158.84 to 557.33)	0.687	0.709	0.134	0.330
FHT	31.50 (24.84 to 35.99)	28.93 (26.85 to 41.07)	33.30 (26.25 to 38.29)	1.942	0.378	-0.135	0.329
WoutAUC	22454.57 (12938.39 to 29406.73)	25091.22 (14283.42 to 35206.22)	29167.97 (18501.77 to 42157.32)	0.687	0.709	-0.200	0.147
WioAUC	22967.65 (13223.69 to 29874.76)	25172.88 (15850.85 to 35361.72)	29454.95 (18687.11 to 42335.48)	0.687	0.709	-0.185	0.181
WoutR	300.37 (213.11 to 395.74)	326.56 (217.61 to 392.31)	353.32 (265.97 to 495.21)	0.687	0.709	-0.157	0.258
FT	68.60 (55.90 to 79.23)	67.97 (64.42 to 93.17)	75.15 (62.50 to 98.85)	2.077	0.353	-0.154	0.266
Rs1090	8.24 (4.33 to 8.76)	9.12 (4.14 to 11.45)	8.76 (5.85 to 10.83)	0.367	0.832	-0.189	0.172
WinR	36.73 (18.20 to 60.62)	29.80 (21.45 to 105.91)	25.33 (13.87 to 47.07)	2.077	0.353	0.157	0.258
Fs50	-0.75 (-1.10 to -0.48)	-0.75 (-1.00 to 0.50)	-0.67 (-0.93 to 0.56)	1.052	0.590	-0.028	0.841
AUC	32655.20 (17724.16 to 41094.57)	31111.52 (21612.44 to 43393.67)	38174.83 (25534.96 to 51066.60)	1.942	0.378	-0.166	0.229
TTP	13.39 (10.32 to 15.83)	13.70 (11.90 to 16.50)	12.37 (10.30 to 14.80)	0.709	0.378	0.125	0.367

^aP < 0.05.

P represents the P value of the median, and P’ represents the P value of the correlation analysis. mTT: Mean transit time; Rs50: Rise slope 50%; IMAX: Maximum intensity; RT: Rise time; WinAUC: Wash-in area under the curve; FHT: Falling half time; WoutAUC: Wash-out area under the curve; WioAUC: Wash-in and out area under curve; FT: Falling time; Rs1090: Rise slope 10%-90%; WinR: Wash-in rate; Fs50: Falling slope 50%; AUC: Area under the curve; TTP: Time to peak; WoutR: Wash-out rate.