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©The Author(s) 2025.
World J Gastrointest Oncol. Jun 15, 2025; 17(6): 106603
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106603
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106603
Table 2 Cox regression analysis for overall survival values
Variable | Category | Univariate analysis | Multivariate analysis | ||
HR (95%CI) | P value | HR (95%CI) | P value | ||
Patients’ characteristics | |||||
Sex | Male/female | 0.66 (0.44-0.99) | 0.0451 | ||
ECOG PS | < 2/≥ 2 | 1.25 (0.84-1.87) | 0.270 | ||
Body mass index | < 25/≥ 25 | 1.42 (0.95-2.13) | 0.084 | ||
Age | < 65/≥ 65 | 1.51 (1.02-2.25) | 0.0401 | 1.59 (1.06-2.39) | 0.0251 |
Tumor grade | < 2/≥ 2 | 0.97 (0.56-1.65) | 0.897 | ||
Tumor location | Right/left | 1.51 (0.87-2.63) | 0.142 | ||
Metastasis status | De novo/recurrence | 1.09 (0.72-1.66) | 0.693 | ||
Liver metastasis | No/yes | 0.99 (0.64-1.54) | 0.976 | ||
Peritoneal metastasis | No/yes | 1.32 (0.81-2.15) | 0.273 | ||
Lung metastasis | No/yes | 0.90 (0.60-1.35) | 0.607 | ||
Metastasectomy | No/yes | 0.42 (0.24-0.71) | 0.0011 | 0.49 (0.29-0.85) | 0.0111 |
Treatment lines | < 3/≥ 3 | 0.86 (0.70-1.07) | 0.168 | ||
Laboratory parameters | |||||
CEA (ng/dL) | < 6.1/≥ 6.1 | 1.70 (1.14-2.55) | 0.0101 | 1.51 (1.00-2.28) | 0.0481 |
CA19-9 (U/mL) | < 21.6/≥ 21.6 | 1.34 (0.91-1.98) | 0.138 | ||
NLR | < 3.09/≥ 3.09 | 1.38 (0.93-2.04) | 0.108 | ||
PLR | < 177.5/≥ 177.5 | 1.57 (1.06-2.33) | 0.0241 | 1.63 (1.09-2.44) | 0.0181 |
SII | < 835.96/≥ 835.96 | 1.67 (1.13-2.46) | 0.0101 | ||
MLR | < 0.38/≥ 0.38 | 1.00 (0.67-1.48) | 0.988 | ||
HRR | < 0.83/≥ 0.83 | 0.64 (0.43-0.95) | 0.0251 | ||
PRR | < 18.85/≥ 18.85 | 1.19 (0.80-1.77) | 0.384 | ||
PDWLR | < 10.87/≥ 10.87 | 1.05 (0.71-1.57) | 0.794 |
- Citation: Zeynelgil E, Duzkopru Y, Kocanoglu A, Karakaya S. Prognostic value of hemoglobin-to-red cell distribution width ratio and inflammation markers in colorectal cancer. World J Gastrointest Oncol 2025; 17(6): 106603
- URL: https://www.wjgnet.com/1948-5204/full/v17/i6/106603.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v17.i6.106603