Charged multivesicular body protein 7 was identified as a prognostic biomarker correlated with metastasis in colorectal cancer

Figure 5 The mRNA of charged multivesicular body protein 7 was down-regulated in colorectal cancer. A: The expression of charged multivesicular body protein 7 (CHMP7) between tumor and normal tissues in colorectal cancer datasets from Gene Expression Omnibus and TCGA_GTEx_COAD; B: The expressions of CHMP7 between metastatic and non-metastatic colorectal cancer samples in datasets from Gene Expression Omnibus and TCGA_COAD; C: The correlation between CHMP7 expression and tumor stage; D: Copy number variations of CHMP7 in TCGA_COAD samples. ^aP < 0.05, ^cP < 0.001, ^dP < 0.0001. CHMP7: Charged multivesicular body protein 7; TPM: Transcripts per million; N: Normal; T: Tumor; M: Metastatic tumor; TCGA: The Cancer Genome Atlas; COAD: Colon adenocarcinoma.