Potential mechanism of Camellia luteoflora against colon adenocarcinoma: An integration of network pharmacology and molecular docking

Figure 3 The expression of hub genes in colon adenocarcinoma patients. Gene expression data from 275 colon adenocarcinoma (COAD) and 349 normal colon cases in the TCGA and GTXx database was used to relationship between the gene expression and the patients prognosis. Compared with the normal groups, the expression of TP53 was significantly increased in the COAD tissues (^aP < 0.05) but there were no statistically significant differences in the expressions of STAT3, ESR1, MAPK8, AKR1C3, RELA, CYP19A1 and JUN in the COAD tissues (P > 0.05).