Efficacy and safety of donafenib plus transarterial chemoembolization and immunotherapy for hepatocellular carcinoma

doi:10.4251/wjgo.v17.i6.105170

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastrointest Oncol. Jun 15, 2025; 17(6): 105170
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105170

Table 1 Baseline clinicopathological parameters of enrolled patients

Parameters	No.
Age (years)
≤ 65	23
> 65	7
Gender
Male	29
Female	1
HBV infection
Yes	29
No	1
HCV infection
Yes	0
No	30
Child–Pugh score
A	28
B	2
AFP (ng/mL)
≤ 400	17
> 400	13
PIVKA (mAU/mL)
Median level	1423.50
ECOG-PS
0	29
1	1
BCLC stage
B	4
C	26

HBV: Hepatitis B virus; HCV: Hepatitis C virus; BCLC: Barcelona Clinic Liver Cancer; AFP: Alpha-fetoprotein; ECOG-PS: Eastern Cooperative Oncology Group Performance Status; PIVKA: Protein induced by vitamin K absence.

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Citation: Yang ZH, Liu SN, Chu FY, Yang C, Chen X. Efficacy and safety of donafenib plus transarterial chemoembolization and immunotherapy for hepatocellular carcinoma. World J Gastrointest Oncol 2025; 17(6): 105170
URL: https://www.wjgnet.com/1948-5204/full/v17/i6/105170.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i6.105170

Yang ZH, Liu SN, Chu FY, Yang C, Chen X. Efficacy and safety of donafenib plus transarterial chemoembolization and immunotherapy for hepatocellular carcinoma. World J Gastrointest Oncol 2025; 17(6): 105170 [PMID: 40547138 DOI: 10.4251/wjgo.v17.i6.105170]

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