Circulating exosomal miR-17-92 cluster serves as a novel noninvasive diagnostic marker for patients with gastric cancer

Figure 4 Expression levels of carcinoembryonic antigen and carbohydrate antigen 19-9 in serum samples of patients with gastric cancer and healthy controls and their clinical diagnostic values alone or with serum exosomal miRNAs. A: Expression level of carcinoembryonic antigen (CEA); B: Expression level of carbohydrate antigen 19-9 (CA19-9); C: Receiver operating characteristic curve (ROC) curve for CEA; D: ROC curve for CA19-9; E: ROC curve for CEA + CA19-9; F: ROC curve for miR-17 + miR-18 + miR-19a + miR-92 + CEA + CA19-9. ^aP < 0.05; AUC: The area under the curve; CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9.