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©The Author(s) 2025.
World J Gastrointest Oncol. May 15, 2025; 17(5): 104076
Published online May 15, 2025. doi: 10.4251/wjgo.v17.i5.104076
Published online May 15, 2025. doi: 10.4251/wjgo.v17.i5.104076
Table 2 Summary of N6-methyladenosine modification of noncoding RNAs in colorectal cancer
METTL3 expression | M6A modified ncRNAs | Function of METTL3 | Ref. |
Upregulation | SNHG1 | Cell proliferation | Xu et al[84] |
Upregulation | FAM83H-AS1 | Cell proliferation | Luo et al[85] |
Upregulation | pri-miRNA-1246 | Cell invasion and migration | Peng et al[78] |
Upregulation | circ1662 | Cell invasion and migration | Chen et al[86] |
Upregulation | POU6F2-AS1 | Metabolism | Jiang et al[87] |
Upregulation | miR-181b-5p | Drug resistance | Pan et al[88] |
Upregulation | Circ0124554 | Drug resistance | Zhong et al[89] |
- Citation: Liao JN, Ni WJ, Wu PH, Yang YD, Yang Y, Long W, Xie MZ, Zhu XZ, Xie FH, Leng XM. Switching from messenger RNAs to noncoding RNAs, METTL3 is a novel colorectal cancer diagnosis and treatment target. World J Gastrointest Oncol 2025; 17(5): 104076
- URL: https://www.wjgnet.com/1948-5204/full/v17/i5/104076.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v17.i5.104076