Using bioinformatics methods to elucidate fatty acid-binding protein 4 as a potential biomarker for colon adenocarcinoma

Figure 3 Screen for immune modules and genes related to fatty acid-binding protein 4 in colon adenocarcinoma tissues. A: Volcano plot of differentially expressed genes (DEGs) between colon adenocarcinoma (COAD) tissues and normal tissues in The Cancer Genome Atlas (TCGA) database; B: Heatmap of DEGs between COAD tissues and normal tissues in TCGA database; C: Calculation of the scale-free fit indices of various soft-thresholding powers (β) and analysis of the mean connectivity of various soft-thresholding powers (β); D: DEGs were clustered based on the dissimilarity measure (1-TOM) and divided into 10 modules; E: Clustering dendrogram of COAD patients; F: A correlation heatmap between module eigengenes and immune parameters (fatty acid-binding protein 4 was used as the main research object) in patients with COAD; G: Scatter plot of the turquoise module eigengenes. COAD: Colon adenocarcinoma; DEGs: Differentially expressed genes; TCGA: The Cancer Genome Atlas.