Metastatic lymph node distribution and pathology correlations in upper and lower gastric cancer patients: A multicenter retrospective study

Table 1 Comparative analysis of clinicopathological factors in upper vs lower gastric cancer, n (%)

Variables	Upper GC	Lower GC	χ²	P value
Gender			2.582	0.108
Male	554 (67.8)	635 (64.2)
Female	263 (32.2)	354 (35.8)
Age (year)			0.485	0.486
< 60	277 (33.9)	320 (32.4)
≥ 60	540 (66.1)	669 (67.6)
Tumor diameter (cm)			61.410	< 0.001a
< 4	453 (55.4)	723 (73.1)
≥ 4	364 (44.6)	266 (26.9)
Pathological type			1.941	0.379
Adenocarcinoma	654 (80.0)	813 (82.2)
Signet-ring cell carcinoma	139 (17.0)	155 (15.7)
Other	24 (2.9)	21 (2.1)
Histological grade				0.018a
G1	42 (5.1)	82 (8.3)
G2	234 (28.6)	295 (29.8)
G3	541 (66.2)	612 (61.9)
pT stage				< 0.001a
T1	163 (20.0)	269 (27.3)
T2	127 (15.5)	131 (13.2)
T3	267 (32.7)	473 (47.8)
T4	260 (31.8)	116 (11.7)
pN stage				< 0.001a
N0	340 (41.6)	429 (43.4)
N1	124 (15.2)	303 (30.6)
N2	135 (16.5)	152 (15.4)
N3	218 (26.7)	105 (10.6)
pTNM stage				< 0.001a
I	354 (43.3)	455 (46.0)
II	50 (6.1)	115 (11.6)
III	413 (50.6)	419 (42.4)
Vascular invasion			4.642	0.031a
Positive	527 (64.5)	589 (59.6)
Negative	290 (35.5)	400 (40.4)
Surgery type			3.370	0.066
PG	656 (80.3)	827 (83.6)
TG	161 (19.7)	162 (16.4)
Chemotherapy			58.041	< 0.001a
Yes	448 (19.7)	713 (72.1)
No	369 (45.2)	276 (27.9)

^aP < 0.05.

GC: Gastric cancer; PG: Partial gastrectomy; TG: Total gastrectomy; TNM: Tumor-node-metastasis.