Clinical characteristics and prognostic analysis of three hundred and nineteen cases of primary gastrointestinal diffuse large B-cell lymphoma

doi:10.4251/wjgo.v17.i12.113661

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Dec 15, 2025; 17(12): 113661
Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113661

Table 2 Least absolute shrinkage and selection operator coefficient of characteristics

Characteristics	LASSO (minute)
Age > 60 years	0.191848352
Gender	-0.219651952
ECOG ≥2	0.360853083
Extranodal invasion site ≥ 2	-0.123956342
β2-MG > 2.2 mg/L	0.230048478
LDH > 250 U/L	0.161655196
B symptoms	0.283986826
Lesion type	-0.19044022
Tissue origin	0.033236256
BCL-6	-0.15250168
MUM-1	0.295835406
BCL-2	-0.135437307
CD5	0.191848352

LASSO: Least absolute shrinkage and selection operator; ECOG: Eastern Cooperative Oncology Group; β2-MG: β2-microglobulin; LDH: Lactate dehydrogenase; BCL-6: B-cell lymphoma 6; MUM-1: Multiple myeloma oncogene 1; BCL-2: B-cell lymphoma 2.

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Citation: Ma JJ, Zhang H, Wang CC, Ji WL, Zhao Y, Li XX. Clinical characteristics and prognostic analysis of three hundred and nineteen cases of primary gastrointestinal diffuse large B-cell lymphoma. World J Gastrointest Oncol 2025; 17(12): 113661
URL: https://www.wjgnet.com/1948-5204/full/v17/i12/113661.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i12.113661

Ma JJ, Zhang H, Wang CC, Ji WL, Zhao Y, Li XX. Clinical characteristics and prognostic analysis of three hundred and nineteen cases of primary gastrointestinal diffuse large B-cell lymphoma. World J Gastrointest Oncol 2025; 17(12): 113661 [PMID: 41480199 DOI: 10.4251/wjgo.v17.i12.113661]

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