Safety and efficacy of cryoablation in treating locally advanced pancreatic cancer

Table 4 Comparison of efficacy indicators before and after cryoablation

Variables	Preoperative	Postoperative day 7	P value	Postoperative day 30	P value
CA199 (U/mL)	542.10 ± 309.56	518.16 ± 297.83	0.340	159.30 + 120.79	0.001
CD4+ T cells (cells/μL)	510.91 ± 120.63	714.08 ± 229.63	0.014	811.75 ± 222.92	0.000
CD8+ T cells (cells/μL)	268.67 ± 43.05	266.33 ± 47.26	0.319	261.58 ± 45.58	0.189
Natural killer cells (cells/μL)	153.83 ± 33.25	197.83 ± 33.92	0.000	190.17 ± 36.97	0.012
TNF-α (pg/mL)	0.71 ± 0.20	1.38 ± 0.41	0.000	1.36 ± 0.33	0.000
Pain scores	5.08 ± 2.47	5.67 ± 1.50	0.189	2.58 ± 1.39	0.000
Tumor size on CT (cm)	3.79 ± 0.90			3.13 ± 0.53	0.001

CA199: Carbohydrate antigen 19-9; CD: Cluster of differentiation; TNF-α: Tumor necrosis factor-α; CT: Computed tomography.