Preliminary exploration of programmed death 1 inhibitor combined with fruquintinib and docetaxel for advanced colorectal cancer

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Dec 15, 2025; 17(12): 112548
Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.112548

Table 3 Adverse events in 13 patients with advanced microsatellite stable/proficient mismatch repair colorectal included in this study, n (%)

Adverse events	Grade 1	Grade 2	Grade 3	Grade 4
Nausea	0	2 (15.4)	0	0
Neutropenia	3 (23.1)	0	0	0
Fatigue	1 (7.7)	1 (7.7)	0	0
Rash	1 (7.7)	1 (7.7)	0	0
Hypothyroidism	1 (7.7)	0	0	0
Lower gastrointestinal hemorrhage	0	0	1 (7.7)	0
Immune-related myocarditis	0	1 (7.7)	0	0

Citation: Meng XY, Cai YM, Sun NN, Zhang WH, Cui RX, Zhang L, Zheng CC, Sun Z, Luo WX, Wang FW. Preliminary exploration of programmed death 1 inhibitor combined with fruquintinib and docetaxel for advanced colorectal cancer. World J Gastrointest Oncol 2025; 17(12): 112548
URL: https://www.wjgnet.com/1948-5204/full/v17/i12/112548.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i12.112548

Meng XY, Cai YM, Sun NN, Zhang WH, Cui RX, Zhang L, Zheng CC, Sun Z, Luo WX, Wang FW. Preliminary exploration of programmed death 1 inhibitor combined with fruquintinib and docetaxel for advanced colorectal cancer. World J Gastrointest Oncol 2025; 17(12): 112548 [PMID: 41480198 DOI: 10.4251/wjgo.v17.i12.112548]

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